Question

3.

An individual who is XX, and secretes high testosterone levels from the adrenal glands during development, will have the following phenotype (morphology):

Select one:

a. testes and female-like genitalia

b. ovaries and male-like external genitalia, with only Wolffian duct differentiation

c. testes and male-like genitalia

d. ovaries and female-like genitalia

e. ovaries and partially masculinized external genitalia, with both Wolffian and Mullerian duct differentiation

4.

An individual who is XY, but does not produce 5 alpha reductase enzyme, will have the following phenotype (morphology):

Select one:

a. ovaries and female-like internal and external genitalia

b. testes and partially feminized external genitalia, with only Wolffian duct differentiation

c. testes and male-like external genitalia, with only Mullerian duct differentiation

d. testes and partially feminized external genitalia, with both Wolffian and Mullerian duct differentiation

e. ovaries at birth that become testes at puberty

Answer 1

Concept:- development of ovary or testist in a developing foetus depends upon presence or absence of SRY gene which is present of Y chromosome. So if y chromosome absent --- ovary develop.

But development of external genitalia depends upon presence or absence of Dihydrotestosterone. Which is formed from Testosteron by 5 Alpha reductase.

If mullarian inhibiting substance is released by Sertoli cell of testis --- then no deffirentiation of mullarian duct.

And presence of androgen stimulate wolfian duct differentiation.

Ans:- 3:- e. ovaries and partially masculinized external genitalia, with both Wolffian and Mullerian duct differentiation.

Since no sry gene so ovary develop.

No stertoli cell so no mullarian inhibiting substance so mullarian duct deffirentiation OCCURE.

Since androgen is present so wolfian duct will also deferentiate.

During embryonic period both male and female have same ext genitalia appearance . Then testosterone is formed by testis which decide the decenretiation of external genitalia.

So if testosterone level will me high then it will lead to masculanized external genitalia.

Ans:-4:-

b.)testis and partially feminized external genitalia, with only Wolffian duct differentiation

Since Y chromosome present --- testis.

Sertoli cell present in testis so mullarian duct will not deferentiate.

Androgen present so Wolffian duct deferentiation present.