Autonomic nervous
system: It is a division of the peripheral nervous
system that controls and regulates the internal organs without any
conscious recognition or effort by the organism. The autonomic
nervous system is a control system that acts largely unconsciously
and regulates bodily functions
- It is formed by collections of motor neurons (ganglia) situated
in the head, neck, thorax, abdomen, and pelvis, and to the axonal
connections of these neurons.
- The organization of ANS is on the basis of the reflex arc and
it has an afferent limb, efferent limb, and a central integrating
system.
- The afferent limb transmits information from the periphery to
the central nervous system (CNS). The receptors are present in the
abdominal and thoracic viscera.
- The efferent limb is made up of preganglionic and
post-ganglionic fibres and an autonomic ganglion.
- The efferent limb is further subdivided based on its anatomic
and physiological differences into sympathetic and
parasympathetic components.
Sympathetic Nervous
system: It connects the internal organs to the
brain by spinal nerves. When stimulated these nerves prepare the
organism for stress. The sympathetic division typically functions
in actions requiring quick responses and is thus known as "fight or
flight" system
Parasympathetic nervous
system: The nerve fibers of the parasympathetic
system are the cranial nerves, primarily the vagus, and the lumbar
spinal nerve when stimulated to increase digestion and reduces
heartbeat. The parasympathetic system is often considered the "rest
and digest" or "feed and breed" system.
Circulation:
SNS:
- When stimulated it increases the circulation.
- It increases the heart rate by stimulating the (β1, β2)
adrenergic receptors.
- It increases the contractility by stimulating the (β1, β2)
adrenergic receptors.
- The SNS acts on β1 adrenergic receptors to increase
chronotropy, dromotropy, and inotropy of the heart
- It also increases conduction velocity.
- By stimulating Adrenergic receptors α1, α2 it stimulates the
vasoconstriction of arterioles and systemic veins.
- It diverts blood flow away from the GI and skin by
vasoconstriction in their vessels.
- By stimulating β receptors it brings the vasodilation of the
coronary vessels of the heart.
- It increases blood flow to the skeletal muscles and lungs by
vasodilatation.
PNS:
- When stimulated it decreases the circulation.
- Decrease heart rate.
- Decrease contractility
- Decrease conduction velocity
- The parasympathetic fibers are responsible for decreasing
chronotropic, dromotropy, and inotropy via cholinergic action on
cardiac M2 receptors.
- stimulates vasodilation
- increases blood flow to the GI.
Respiration:
SNS:
- It increases the respiratory rate to meet with the increased
demand of oxygen by the muscles.
- Increased vascular resistance is mediated by α-adrenoreceptors
upon sympathetic nerve stimulation.
- stimulation of (β2) brings the Bronchodilatation
- It dilates bronchioles through circulating epinephrine and this
allows for greater alveolar exchange.
- Chemoreceptors respond to decreased arterial PO2 levels to
increase sympathetic nerve stimulation by the sympathetic chain
neurons
PNS:
- It decreases the respiratory rate.
- Parasympathetic activation via vagal stimulation results in
cholinergic-mediated relaxation of pulmonary arteries.
- It stimulates the constriction of the bronchiolar diameter when
the need for oxygen has diminished
Digestion:
SNS:
- It decreases the blood flow to the GI.
- Decrease activity of the digestive system
- Inhibits peristalsis and decreases intestinal tone.
- Decreases amount of secretion by digestive glands
- It causes glucose to be released to blood from the liver.
- Constricts all the intestinal sphincters by stimulating α
receptors.
- It increases Basal metabolism.
PNS:
- It stimulates GI by dilating blood vessels leading to the GI
tract, increasing the blood flow.
- Stimulates salivary gland secretion.
- Accerates peristalsis.
- Increases the tone
- stimulates increased digestion of food and, indirectly, the
absorption of nutrients.
- Stimulates relaxation of the sphincter
Excretion:
SNS:
- Stimulates to produce perspiration
- Decreases urine output by Increasing renin secretion by
stimulation of (β1) receptors
- Constricts urethral sphincter by stimulation of α1
receptors.
- Brings Detrusor relaxation by stimulation of β2 receptors.
PNS:
- Brings Detrusor contraction
- Stimulates Sphincter relaxation
- No effect on preparation or urine output.