Question

In: Anatomy and Physiology

What would you expect to happen to the volume of urine produced after consuming hypo- or...

  1. What would you expect to happen to the volume of urine produced after consuming hypo- or hypertonic drinks? Explain why you expect an increase, decrease or no change in urine volume.
  1. Group 1 (water)
  1. Group 2 (Gatorade / isotonic sports drink)
  1. Group 3 (salty broth)

Solutions

Expert Solution

For solving this question we are assuming that the drink offered is completely absorbed in the gut wall

Group 1 - Water -( plain water with no salt and carbohydrates)

  • Water compared to blood is hypotonic.
  • Water when it enters the blood vessels it causes volume gains.
  • Water has a tendency to move from areas of low osmolarity to areas of high osmolarity.
  • Consumption of water expands the intravascular volume.
  • As it doesn't provide any salt with it, it dilutes the intravascular volume.
  • In other words, it reduces the osmolarity of the intravascular compartment.
  • Now, the interstitium and the intracellular compartment has higher osmolarity.
  • Therefore, fluid from the intravascular compartment moves to the interstitium and the intracellular compartment.
  • These reduce the blood volume and increase the blood osmolarity
  • This triggers the release of anti-diuretic hormone
  • This reduces the fluid loss from the kidney and concentrated urine is excreted.
  • The volume of urine reduces

Group 2

  • the osmolarity of the isotonic drinks is the same as blood.
  • Therefore, the solute concentration in the intravascular and interstitium and intracellular compartments is the same.
  • So there is no movement of fluid between the compartments
  • However, the act drinking isotonic solution has expanded the intravascular compartment.
  • there is also reduce plasma osmolarity due to dilution
  • This inhibits anti-diuretic hormone release
  • The urine output increases

Group 3

  • The solute content of a hypertonic solution is more than that of the intra-cellular and interstitium.
  • As a result, the water moves from the intracellular and interstitium to the intravascular compartment.
  • this causes volume expansion.
  • This inhibits anti-diuretic hormone.
  • therefore the urine-output increase.
  • In addition, the excretion of sodium also increases.

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