Answer
- The loop of Henle facilitate formation of concentration
gradient by establishment of countercurrent
multiplier.
- There are two segments of loop of Henle.
- Ascending limb of loop of Henle is
permeable to NaCl but is impermeable to water. As
a result NaCl diffuses out in the interstitial fluid.
- Interstital fluid becomes much concentrated and creates a
gradient to reabsorb water from descending limb. The
descending limb of loop of Henle is
permable to water but not to NaCl.
- Also, as interstitial fluid has more NaCl concentration than in
the fluid entering collecting duct, water diffuses from
collecting duct into the interstitum.
- This helps in concentrating the urine.
Also, as terminal part of collecting duct is permeable to urea, it
is reabsorbed and enters interstitium.
Hence, urea also contributes to increase insterstitial
osmolarity aiding water reabsorbtion.
Hence, loop of Henle is a loop and not a straight
line.