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In: Anatomy and Physiology

2 Example of these pairs: In myeloid cells, pair of cell types; one being a circulating...

2 Example of these pairs:

In myeloid cells, pair of cell types; one being a circulating form and the other is similar, but a resident tissue version

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2 Example of these pairs:

In myeloid cells, pair of cell types; one being a circulating form and the other is similar, but a resident tissue version

Myeloid refers to the sense of bone marrow, therefore myeloid tissue is the tissue of bone marrow. It also includes the bone marrow cell lineage or resembling bone marrow also called as myelogenous tissue. The precursor of the myeloid lineage is the hematopoietic stem cells, which also gives rise to lymphoid lineage and they both together involve in  dendritic cell formation.

Cells of myeloid lineage are monocytes, macrophages, neutrophils, basophils, eosinophils, erythrocytes, dendritic cells and megakaryocytes to platelets.

Circulating form of myeloid cells are: granulocytes, monocytes, macrophages, and dendritic cells that circulate through the blood and lymphatic system. They rapidly attracted to the site of infection via various chemokine receptors.

Resident tissue myeloid cell type is the presence of resident macrophages in many organs observed during embryonic development. They are capable of self-renew independently from blood monocytes. On contrary circulating machrophages are mostly derived from monocytes. Tissue resident machrophages play role under inflammatory conditions either together with circulating ones or replaced by recruited monocyte-derived macrophages.


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