Question

With a relevant example, describe and illustrate the organisation of neuroendocrine control, and explain its significance.

Answer 1

Neuroendocrine system is basically made up of neuroendocrine cells .Neuroendocrine cells comprises of nerve cells known as neurons and endocrine cells which is involved in regulating hormones release by receiving the signals from nerve cells .Ultimately hormones act on different parts of the body .
Example of neuroendocrine integration is Of Hypothalamus pituitary adrenal axis .
Normally Hypothalmus produces trophic hormones factors ( Thyrotropin releasing hormone TRH,CRH corticotropin releasing hotmone )which will go and act on pituitary glands and it will release various hormones like ( Thyroid stimulating hormone , Adrnocorticotropic hormones ) which will finally act on respective glands like Thyroid ,adrenal medulla to release thyroid hormones ,and adrenaline in blood which will exerts its further actions .So any abnormality in hypothalmus it will not release the trophic hormones and no Further release from pituitary and target organs and no further actions on various parts of the body .
So in absence of TSH pateint may develop hypothyroidism freatures ( Cold intolerance ,lethargy ) and no release of adrenaline will not allow the body to cope up with stress .Hence in this way neuroendocrine system is integrated and work hand in hand .