Question

You have two mutant cells, in which the first mutant cell cannot form dimers, and the second mutant cell lacks the kinase function. What would happen if you if you add Receptor tyrosine kinases (RTK-s) signals to these overexpressed cells, when these two mutant cells already have the Receptor tyrosine kinases already, and respond normally to signals in signal transduction. What will happen in terms of signal transduction in these two cells?

Will two mutated cells, one with no kinase function and the other cannot properly form dimers, be able to show signal transduction if you add RTK-signals?

Answer 1

Signal transduction ia the process by which a chemical or physical signal is transmitted through a cell as a series of molecular event.

Tyrosine kinase is an enzyme that specifically phosphorylates tyrosine amino acid .while signal transduction extracellular ligand binds typically to form dimers.tyrosine in cytoplasmic portion of each receptor monomer to be trans phosphorylated by partner receptor propogating signal through plasma membrane it activetes the activity thid a little lower functioning of dimer do not afftect the signal transduction.

Cells that lack kinase function cannot show kinase activity but when we add the kinase from outside to make them active the signal transduction can be seen..mutation causes the cells to lose its function but when the required component added from outside helps restore its function that is needed.