An extracellular signal, such as Epinephrine, acting through a G-protein coupled receptor can have quite different...

An extracellular signal, such as Epinephrine, acting through a G-protein coupled receptor can have quite different effect depending on multiple factors. Indicate at least 3 factors that would be responsible of these various cellular responses from a single extracellular signal.

Solutions

Expert Solution

This cell signalling pathway depends on following factors during transformation of signal from extracellular environment to intracellular.

they are

1.Signal reception by cell membrane receptor:

2. Second messengers:The level of second messengers, such as Ca2+, cAMP, and IP3 are modulated in response to binding of ligand to cell-surface receptors. These, in turn regulate the activities of enzymes and nonenzymatic proteins.

Also the same signaling molecule may produce different results depending on what molecules are already present in the cell

3. Protein phosphorylation: protein activity is altered by the addition of a phosphate group to one or more sites on the protein

phosphorylation will make a protein more active in some cases and in other cases, phosphorylation may inactivate the protein or brake down it.

4. Signal termination by protein phosphatase

gladiator answered 1 year ago

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