In: Biology
True or False? If false, explain why.
a) The ribosome moves along the mRNA in a 5’ à 3’ direction
b) The overall structure of the ribozyme is dictated by rRNA
c) Ribosomes consist of 2/3 protein and 1/3 rRNA
d) Each ribosome has 1 large subunit and one small subunit
e) The small ribosomal subunit is the first to bind to the mRNA via the 5’ cap
f) RNA polymerase II is responsible for transcribing messenger RNA •
g) Combinatorial control of gene expression involves groups of transcriptional regulators working together to determine the expression of a gene
h) A nonsense mutation is a type of base pair substitution that leads to a change from one amino acid to a different amino acid.
a) The ribosome moves along the mRNA in a 5’ à 3’
direction
The answer is
True. Because the ribosomal binding regions such as kozak sequece
is present at 5' side of the mRNA, it hinds there ans starts the
translocation.
b) The overall structure of the ribozyme is dictated by
rRNA
The answer is
True. The fucntion of ribozyme is a part of the large subunit
ribosomal RNA.
c) Ribosomes consist of 2/3 protein and 1/3 rRNA
The answer is
False, becuase ribsome is composed with 60% rRNA and 40% protein
which means 2/3 portion of rRNA and 1/3 portion of
protein.
d) Each ribosome has 1 large subunit and one small subunit
The answer is
True. Each ribosome is composed wiht two subunits they are reffered
as large and small subunits.
e) The small ribosomal subunit is the first to bind to the mRNA
via the 5’ cap
The answer is
True. The small subunit of ribsome binds to the 5' utr region first
along with transcription factor to intitiate the
translation.
f) RNA polymerase II is responsible for transcribing messenger
RNA
The answer is
True.
RNA pol I synthesizes rRNA,
RNA pol II synthesizes mRNA,
RNA pol III synthesized tRNA.
h) A nonsense mutation is a type of base pair substitution that
leads to a change from one amino acid to a different amino
acid.
The answer is
False. If mutation leads to change from one AA to other, it is
reffered as missence mutation.