Briefly explain how the lagging strand is replicated. Include
how the replication starts, the enzymes involved...
Briefly explain how the lagging strand is replicated. Include
how the replication starts, the enzymes involved and the completion
of the lagging strand replication
What does “semi-discontinuous” DNA replication mean? Explain in
words how the lagging DNA strand is replicated in bacteria. What
specific enzymatic activities does DNA polymerase I have? Name each
activity and explain its role in DNA replication. If DNA polymerase
I lacked its 3’-5’ exonuclease activity, what specific consequences
with respect to DNA replication would be observed? What
consequences would be observed if, instead of DNA pol I, DNA
polymerase III lacked its 3’-5’ exonuclease activity? Explain your
answers.
Describe the synthesis of an Okazaki fragment on the lagging
strand in a replication fork. Include names of enzymes and the
proper 5’ and 3’ ends of DNA strands.
1.Describe the synthesis of the leading strand for DNA replication.
2. How the lagging strand differ from the leading
strand?
3. what is semiconservative replication?
At the end of replication, about 100 nucleotides remain
unreplicated on the lagging daughter strand. What mechanism (and
what enzyme) in eukaryotes solves the problem of shortened DNA
ends?