Question

What are the general differences between granulomatous amoebic encephalitis and PAM? [etiological agent, progression, susceptibility]

Answer 1

granulomatous amoebic encephalitis :
etiology - Acanthamoeba are naturally occurring amoeba (tiny, one-celled animals) commonly found in water sources, such as tap water, well water, hot tubs, and soil and sewage systems. If these tiny parasites infect the eye, Acanthamoeba keratitis results.
Acanthamoeba can also cause disseminated infection by entering the skin through a cut, wound, or through the nostrils. Once inside the body, the amebas travel through the bloodstream to other parts of the body, especially the lungs, brain, and spinal cord
symptoms :

• Eye pain.
• Eye redness.
• Blurred vision.
• Sensitivity to light.
• Sensation of something in the eye.
• Excessive tearing.

PAM -

etiology -  Naegleria fowleri is a free-living microscopic ameba*, (single-celled living organism). It can cause a rare** and devastating infection of the brain called primary amebic meningoencephalitis (PAM).
Naegleria fowleri lives in freshwater habitats by feeding on bacteria. However, in rare instances, the ameba can infect humans by entering the nose during water-related activities. Once in the nose, the ameba travels to the brain and causes a severe brain infection called primary amebic meningoencephalitis (PAM), which is usually fatal.
symptoms :

• Severe frontal headache
• Fever
• Nausea
• Vomiting
  
• Stiff neck
• Seizures
• Altered mental status
• Hallucinations
• Coma