Question

16. How would you expect the mitotic index of cancer tissue to compare with that of a normal cell?

17.   What structure(s) is(are) responsible for movement of chromosomes during the mitotic process?

18.   Where in your body is mitosis occurring at the fastest rate? How is this different from roots?

20.   In the treatment of cancer, a drug called colchicine is sometimes used. Colchicine stops cell division at metaphase. What effect might this treatment have on cancer patients?

Answer 1

16. Answer:-

Mitotic index is the calculation of undergoing cells to mitotic division with respect to the total number of cells. i.e ( Prophase +Metaphase +Anaphase +Telophase)/N × 100%, where N is the total n number of cells.

When a tissue became cancerous then more number of cells go to unrestricted division, whereas in the case of normal tissue the number of cells undergoing mitotic division is less.  

In case of cancerous tissue the checkpoints of the cell can not control the faulty cells to go under division, cells vigorously undergo division in less time, so that the cells became abnormal compare to the normal cells. E.g, if normally 10 cells of normal tissue undergo division then in case of cancer tissue it will be 550 above.

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