Question

Provide a simple explanation as to how a virus might be generated in which more than one env protein can be incorpoorated into a retrovirus particle by considering the process of budding.

Answer 1

viruses maturation is done by budding at cellular membrane. It have been thought that this procedure is done by interactions with in the viral transmembrane protein and internal vireos component like core, capsid, or nucleocapsid.

the core protein of retrovirus are able to form enveloped particle itself. And Also, budding of negetive-strand RNA viruse like orthomyxoviruses,and paramyxoviruses seem to be accomplish by internal components, or by matrix protein, so the spike proteins are not require for budding of these viruse.

In contrast, budding virus particles may occur in the absence of the nucleocapsid and show to required two membrane proteins. For study this process by forming a three-dimensional protein lattice on the surface or within the membrane.

It is also discovered that the alphavirus spike proteins are engage in extensive and lateral interactions,for the formation a dense protein shell on outer surface of viral envelope. according this data, the budding of enveloped viruse in general is govern by lateral interaction within peripheral and integral membrane proteins.

So tis mechanism show that how env protein could be incorpoorated into a retrovirus particle by the process of budding.

The image related to this concept is shown below-