4. Glycogen Synthesis
a) What is the role of Glycogenin in glycogen synthesis?
b) Which enzymes regulate glycogen synthesis and degradation
(directly or indirectly)?
c) Hers disease is caused by mutations in the liver form of
glycogen phosphorylase and often has mild symptoms. In contrast von
Gierke disease, which is caused by mutations in glucose
6-phosphatase, has severe symptoms including severe hypoglycemia
(low blood sugar). Based on your knowledge of glycogen and glucose
metabolism, why does von Gierke disease have...