Draw a diagram showing how valinomycin generates a proton motive force. Explain.

Expert Solution

Valinomycin is a mobile ion carrier that trasports K+ down its electrochemical gradient. They act as uncouplers that uncouple electron transport by creating electrical short circuits. It forms a lipid-soluble complex with potassium ion that readily passes through the inner mitochondrial complex. This influx of positive ions neutralizes the negative charges inside the mitochodrial matrix that reduces the proton motive force. In this way, valinomycon blocks ATP synthesis without blocking the the electron transfer to O2.

gladiator answered 2 years ago

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