Question

In: Biology

1.Which of the following medications, when taken prior to eating, is especially effective for correcting postprandial...

1.Which of the following medications, when taken prior to eating, is especially effective for correcting postprandial hyperglycemia after a high-carbohydrate meal, so that hypoglycemia post dosing is minimized?

Acarbose

Glyburide

Glitazone

Tolbutamide

2. Which of the following best describes the outcome resulting from the use of 17alpha-alkylated testosterone to enhance athletic performance?

Decreased hepatotoxicity compared with testosterone esters

Decreased spermatogenesis

Reduced effects on serum lipid levels compared with testosterone esters

Cannot be converted to DHT, which reduces effects on prostate size

3. Which one of the following is most likely to interfere with cytochrome P450 metabolism?

Cimetidine

Ranitidine

Sucralfate

Metoclorpramide

4. A 28-year-old patient is newly diagnosed with active TB. Which of the following drug combinations should be initiated in this patient?

Ethambutol, pyrazinamide, rifampin, streptomycin

Ethambutol, isoniazid, rifampin, streptomycin

Ethambutol, pyrazinamide, rifampin, streptomycin

Isoniazid, rifampin, pyrazinamide, ethambutol

Expert Solution

Answer:

1.Which of the following medications, when taken prior to eating, is especially effective for correcting postprandial hyperglycemia after a high-carbohydrate meal, so that hypoglycemia post dosing is minimized?

Acarbose - Correct Option (Explanation: Acarbose is an anti-diabetic drug to treat type 2 diabetes and delays the digestion of starch and sucrose into monosaccharides in a dose dependent way).
Glyburide
Glitazone
Tolbutamide

2. Which of the following best describes the outcome resulting from the use of 17alpha-alkylated testosterone to enhance athletic performance?

Decreased hepatotoxicity compared with testosterone esters
Decreased spermatogenesis
Reduced effects on serum lipid levels compared with testosterone esters
Cannot be converted to DHT, which reduces effects on prostate size - Correct Option

3. Which one of the following is most likely to interfere with cytochrome P450 metabolism?

Cimetidine - Correct (Explanation: Cimetidine is a potent inhibitor of certain cytochrome P450 enzymes and blocks their activity)
Ranitidine
Sucralfate
Metoclorpramide

4. A 28-year-old patient is newly diagnosed with active TB. Which of the following drug combinations should be initiated in this patient?

Ethambutol, pyrazinamide, rifampin, streptomycin
Ethambutol, isoniazid, rifampin, streptomycin
Ethambutol, pyrazinamide, rifampin, streptomycin
Isoniazid, rifampin, pyrazinamide, ethambutol - Correct Option ( Explanation: New patients are presumed to have drug susceptible TB. For the two month “intensive” TB drug treatment phase they should receive: Isoniazid (H/Inh) with rifampicin (R/Rif) and pyrazinamide (Z/Pza) and ethambutol (E/Emb)

gladiator answered 1 year ago

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