Question

In: Biology

1. In DNA, the type of bonds that form the base pairing between the bases, A::T...

1. In DNA, the type of bonds that form the base pairing between the bases, A::T and C::G are?

a. ionic bonds

b. peptide bonds

c. H-bonds

d. covalent bonds

2. If you wanted to build a short DNA strand, which of the following nucleotides would you not use?

Select one:

a. dTTP

b. dUTP

c. dGTP

d. dCTP

Solutions

Expert Solution

1. Option C is correct : Hydrogen bonds

In DNA, nucleotides are paired to each other via hydrogen bonds in a complementary manner. Adenine pairs with thymine by two hydrogen bonds and cytosine binds with guanine by three hydrogen bonds.These hydrogen bonds function in maintaining the double helical structure of DNA.

2. Option b is correct : dUTP (deoxyuridine triphosphate)

DNA is composed of four nitrogenous bases which are adenine, thymine, guanine and cytosine. During DNA synthesis, these bases are incorporated inside the double helix by DNA polymerase using substrates such as dATP (for adenine), dTTP (for thymine), dGTP (guanine) and dCTP (for cytosine). dUTP resembles UTP (uracil triphosphate) which is required for RNA synthesis. dUTP acts as a substrate for synthesizing various enzymes like nucleoside diphosphate kinase 1, uridine-cytidine kinase, nucleodide diphosphate kinase B.


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