A gene D is linked to its marker G. Linkage means ________________ The marker "G" is...

A gene D is linked to its marker G. Linkage means ________________

The marker "G" is characterized by three single nucleotide polymorphisms (SNPs), the haplotype would be _______________

The researchers tested whether the gene and the marker locus were in linkage equilibrium within a population. Linkage equilibrium is __________

Previous research in this population had determined that there was little inbreeding. Inbreeding is ___________

Expert Solution

Linkage: The tendency for genes to be inherited together as a package because of their location near one another on the same chromosome.

– Consider j binary markers (e.g., SNPs) in a genomic region

– There are 2j

possible haplotypes so in this 3 snps we will have 8 haplotypes.

Linkage equilibrium describes the situation in which the haplotype frequencies in a population have the same value that they would have if the genes at each locus were combined at random. In other words, it occurs when linkage disequilibrium is at zero.

Inbreeding is the production of offspring from the mating or breeding of individuals or organisms that are closely related genetically. ... Inbreeding results in homozygosity, which can increase the chances of offspring being affected by deleterious or recessive traits.

gladiator answered 2 years ago

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