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Tasko is an antimicrobial that interferes with telomerase activity in fungal pathogens. Explain the effects of...

Tasko is an antimicrobial that interferes with telomerase activity in fungal pathogens. Explain the effects of this drug on the yeast and why it is an effective drug.

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Expert Solution

A telomere refers to repetitive nucleotide sequences at each end of a chromosome, which protects the end of the chromosome from deterioration. When telomeres get too short, this  causes the cells to age and stop functioning properly.

Telomerase is an enzyme which maintains the length of telomeres by addition of guanine-rich sequences.

'Tasko' - antimicrobial that interferes with telomerase activity in fungal pathogens

Here, inhibition of telomerase activity prevents the maintenance of telomere length. As a result, telomere may shorten, which causes the cells to age and stop functioning properly leading to apoptosis.

gladiator answered 1 year ago
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