In Glycolysis, fructose-6-phosphate is converted to fructose-1,6-biphosphate by phosphofructokinase. How many of the following statements are...

In Glycolysis, fructose-6-phosphate is converted to fructose-1,6-biphosphate by phosphofructokinase. How many of the following statements are true? this step is reversible this step is a point of control it is activated by ATP only fructose1,6-biphosphate is committed to become pyruvate and yield energy

Solutions

Expert Solution

Reaction 3 of glycolysis , in which fructose-6-phosphate is converted to fructose-1,6-biphosphate is an ATP -dependent phosphorylation which has the following key points:

1) ATP is the phosphate donor

2)It is an irreversible step

3) First committed step with delta G value negative of -14.2 KJ/mol ,commited to become pyruvate and yield energy

4)This reaction is inhibited by both citrate and ATP (as ATP inhibits PFK1 is rather inhibited

5)It is activated by ADP, AMP ,

6)Major control point of glycolysis include phosphofructokinase,pyruvate kinase as well as hexokinase

True statement:fructose-1,6-biphosphate is commited to become pyruvate and yield energy

queen_honey_blossom answered 1 year ago

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