In: Biology
Genetic Disorder: Argininosuccinic Aciduria (use for bottom section)
Mode of Inheritance: By an autosomal recessive trait
Scenario 1 Both parents are afflicted with the genetic disorder. |
Parent Genotypes: Parent Phenotypes: Punnett Square showing the possible offspring: Possible Offspring Genotypes: Possible Offspring Phenotypes: Probability Offspring will be afflicted with the disorder: Explanation of the results: |
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Scenario 2 One parent is afflicted with the genetic disorder, and the second parent does not have the disorder and is not considered a carrier. |
Parent Genotypes: Parent Phenotypes: Punnett Square showing the possible offspring: Possible Offspring Genotypes: Possible Offspring Phenotypes: Probability Offspring will be afflicted with the disorder: Explanation of the results: |
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Scenario 3 One parent is afflicted with the genetic disorder, and the second parent is considered a carrier. |
Parent Genotypes: Parent Phenotypes: Punnett Square showing the possible offspring: Possible Offspring Genotypes: Possible Offspring Phenotypes: Probability Offspring will be afflicted with the disorder: Explanation of the results: |
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Scenario 4 Neither parent is afflicted with the genetic disorder, nor are they considered carrier. |
Parent Genotypes: Parent Phenotypes: Punnett Square showing the possible offspring: Possible Offspring Genotypes: Possible Offspring Phenotypes: Probability Offspring will be afflicted with the disorder: Explanation of the results: |
Answer =
Biology
Genetic Disorder: Argininosuccinic Aciduria (use for bottom section)
Mode of Inheritance: By an autosomal recessive trait
Scenario 1
Both parents are afflicted with the genetic disorder.
Parent Genotypes: aa X aa
Parent Phenotypes: Argininosuccinic Aciduria X Argininosuccinic Aciduria
Punnett Square showing the possible offspring:
a | a | |
a | aa (afflicted) | aa (afflicted) |
a | aa (afflicted) | aa (afflicted) |
Possible Offspring Genotypes: All offspring are aa
Possible Offspring Phenotypes: afflicted with Argininosuccinic Aciduria
Probability Offspring will be afflicted with the disorder: 4/ 4 = 1 = 100%
Explanation of the results: Both the parents are afflicted with Argininosuccinic Aciduriait means they have both the recessive alleles.
therefore all children have both alleles recessive
Hence all childrens are afflicted.
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Scenario 2
One parent is afflicted with the genetic disorder, and the second parent does not have the disorder and is not considered a carrier.
Parent Genotypes: aa X AA
Parent Phenotypes: Argininosuccinic Aciduria X Normal
Punnett Square showing the possible offspring:
a | a | |
A | Aa (Carrier) | Aa (Carrier) |
A | Aa (Carrier) | Aa (Carrier) |
Possible Offspring Genotypes: All offspring are Aa
Possible Offspring Phenotypes: All are carrier
Probability Offspring will be afflicted with the disorder: 4/ 4 = 1 = 100%
Explanation of the results: one of the parents are afflicted with Argininosuccinic Aciduriait while other is normal therefore their childrens have one allele is the recessive alleles.
therefore all children are carrier.
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Scenario 3
One parent is afflicted with the genetic disorder, and the second parent is considered a carrier.
Parent Genotypes: aa X Aa
Parent Phenotypes: Argininosuccinic Aciduria X carrier
Punnett Square showing the possible offspring:
a | a | |
A | Aa (Carrier ) | Aa (Carrier ) |
a | aa (afflicted) | aa (afflicted) |
Possible Offspring Genotypes: Aa (50% ) & aa (50%)
Possible Offspring Phenotypes: Carrier (50% ) & afflicted (50%)
Probability Offspring will be afflicted with the disorder: 2/ 4 = 1 /2 X 100 = 50%%
Explanation of the results: one of the parent is afflicted with Argininosuccinic Aciduriait & other is carrier.therefore 50% of their children are afflicted & 50% are carrier.
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Scenario 4
Neither parent is afflicted with the genetic disorder, nor are they considered carrier.
Parent Genotypes: AA X AA
Parent Phenotypes: Normal X Normal
Punnett Square showing the possible offspring:
A | A | |
A | AA ( Normal) | AA ( Normal) |
A | AA ( Normal) | AA ( Normal) |
Possible Offspring Genotypes: All offspring are AA
Possible Offspring Phenotypes: all are normal
Probability Offspring will be afflicted with the disorder: 0/ 4 = 0%
Explanation of the results: Both the parents are normal therefore they does not have any recessive allele.
therefore all children are normal.