In: Biology
If being a cancer cell was easy every cell would do it. Based on what you learned from this course, using at least 3 distinct points, justify this statement. (5 points)
Answer :
Cancer is a complex genetic disease that is caused by specific changes to the genes in one cell or group of cells. These changes disrupt normal cell function – specifically affecting how a cell grows and divides. In contrast to normal cells, cancer cells don't stop growing and dividing, this uncontrolled cell growth results in the formation of a tumor. Cancer cells have more genetic changes compared to normal cells, however not all changes cause cancer, they may be a result of it. The genetic changes that contribute to cancer usually affect three specific types of gene; proto-oncogenes, tumor suppressor genes, and DNA repair genes
Normal Cell. Cancer cell
Cell shape | Uniform | Irregular |
Nucleus | Spheroid shape, single nucleus | Irregular shape, multi-nucleation common |
Chromatin | Fine, evenly distributed | Coarse, aggregated |
Nucleolus | Single, inconspicuous nucleolus | Multiple, enlarged nucleoli |
Cytoplasm | Large cytoplasmic volume | Small cytoplasmic volume |
Growth | Controlled | Uncontrolled |
Maturation | Mature into specialized cells | Remain immature and undifferentiated |
Blood supply | Normal angiogenesis (occurs during development/ healing) | Tumor-induced angiogenesis |
Oxygen | Favored (for aerobic respiration) but will undergo anaerobic respiration if required | Not required (thrive in hypoxic conditions), favor anaerobic respiration |
Location | Remain in their intended location |
Can spread to different locations in the body (metastasis ) |
These following factors are there which are present in normal amd cancer cell which differentiate the cancer cell to normal cell
so every cell cannot be the cancer cell