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Which of the following statements on INR (international normalization ratio) is (are) correct? A. It is...

Which of the following statements on INR (international normalization ratio) is (are) correct?

A. It is calculated based on PT (prothrombin time)

B. It is calculated on PTT (partial thromboplastin time)

C. It is used to monitor heparin therapy

D. INR values are laboratory-specific, and therefore cannot be compared among different hospitals

Solutions

Expert Solution

A.it is calculated based on PT,C.it is used to monitor heparin therapy.

International normalized ratio is the ratio of prothrombin time of patient to control prothrombin time (which is standardized for the potency of thromboplastin reagent by WHO)

The control prothrombin time is standardized time by WHO so INR is not laboratory specific. But prothrombin time alone is laboratory specific since reagents used vary from one laboratory to another.and so prothrombin time cannot be compared among different laboratory but INR can be.

INR values are used to monitor the effectiveness of anticoagulant therapy. For peoples on warfarin or heparin INR should be monitored daily to keep it in the standard range.

gladiator answered 2 years ago
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