Question

In: Biology

If 1,3-BPG is used as a substrate for gluconeogenesis, how many NTP molecules does it cost...

If 1,3-BPG is used as a substrate for gluconeogenesis, how many NTP molecules does it cost to make one glucose residue in glycogen in this cell? Which NTP?

Solutions

Expert Solution

1, 3 BPG will enter in to gluconeogenesis at level of glyceraldehyde 3 phosphate dehydrogenase.

That will cause 4 ATP molecules utilization in incorporation of 1 glucose molecule in glycogen.

Utilization of 2 NADH in conversion of 1, 3 bis phospho glycerol to glyceraldehyde 3 phosphate.

1ATP form during PFK reaction

ATP FORMED ( 5-1) = total 4 ATP will be utilized

Here calculate 1 NADH = 2.5 ATP

explanation has been attached below


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