11. How does a lack of insulin prevent the cell from using glucose? 12. Why is...

11. How does a lack of insulin prevent the cell from using glucose? 12. Why is it important that specific tissues respond to insulin in different ways? 13. Hypothesize a mechanism to explain how tissues respond to insulin in different ways, even tissues that have the same amount of the receptor.

Expert Solution

Answer: 11

Due to the lack of insulin, insulin receptor on the cell will not bind to the insulin. This will result in no transport of glucose (which is outside the cell) into the cell. As a result, glucose will not be used by the cell. To use the glucose, enough insulin is required.

Answer: 12

Specific tissues may respond to insulin in a different way because each and every tissue or cell has different needs of insulin. The DNA composition of the insulin receptor of cells/tissues are different, DNA encoding of insulin receptors is expressed differently. This ensures that each tissue or cell receives the amount of insulin that it actually needs.

Answer: 13

If the number of receptors is same in two different tissues. In the former tissue, the binding of insulin will result in uptake of glucose, that is a short-term effect. While in the later tissue, the binding of insulin may result in kidney failure, that is a long-term effect.

gladiator answered 1 year ago

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