Question

In: Physics

3. List some types of optimization algorithms for photons and for protons planning. Compare the dose...

3. List some types of optimization algorithms for photons and for protons planning.
Compare the dose distribution of Photon IMRt with the proton IMPT.
How are the organs at risk protected in photon therapy and how are in Proton therapy?

Solutions

Expert Solution

3. Three optimisation methods generally used include KonRad, Broyden-Fletcher-Goldfarb-Shanno (L-BFGS) algorithm and conjugate gradient algorithm (CG).

A study revealed the following whole-body dose distribution:

Specific drugs have been tested, and include amifostine, agents that target the renin-angiotensin system (RAS); angiotensin converting enzyme inhibitors (ACEI) and angiotensin II receptor agonists (AT2RA), genistein, pentoxyfiline, and manganese superoxide dismutase/plasmid liposomes.

They are mostly used for photon therapy and are potently being researched for proton therapy as proton therapy is a pretty new technique.


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