Question

Create a metabolic pathway that begins with palmitoyl coA in the mitochondrial matrix, and ends up pyruvate

You have oxaloacetate, citrate shuttling, ATP, and erythrose-4-phosphate if you need them

Answer 1

Answer : non carbohydrate precursor of glucose are first converted in to pyruvaye or enter the pathway at later intermediate such as oxaloacetate and dihydroxyacetone phosphate. lactate is readily converted in to pyruvate by the action of lactate dehydrogenase.

explanation : transport of pyruvate in to the mitochondria is thriugh the transport protein pyruvate translocase . pyruvate translocase transport pyruvate in a symport fashion with a proton and hence , is active, consuming energy. upon entry in to the mitochondria , the pyruvate is decarboxylated , producing acetyl co- A .

In the presence of oxygen, pyruvate is converted in to acetyl co- A and then enter the citric acid cycle. more ATP can be formed from the breakdown of glucose when oxygen is present.

In human, the most important metabolic pathway are : glycolysis - glucose oxydation in order to obtain. citric acid cycle -- acetyl co - A oxidation in order to obtain GTP and valuable intermediates. oxidative phosphorylation -- disposal of electron released by glycolysis and citric acid cycle.