Describe how subunit cooperativity works in the binding of O2 to hemoglobin in the lungs and...

Describe how subunit cooperativity works in the binding of O₂ to hemoglobin in the lungs and the release of O₂ in the tissues. Include in your response the benefit of subunit cooperativity.

Solutions

Expert Solution

when one molecule binds to the oxygen it changes the shape and 3 heme becomes more likely to attach to the oxygen molecules.Likewise when the oxyhaemoglbin is saturated and there is removal of oxygen molecule this would result cause change in the structure and three molecules are also likely to be dissociated.

Always oxygen travels from high partial pressure to the low partial pressure.As RBC containing the oxygen molecule are at high partial pressure whereas the tissues have low partial pressure and so the oxygen is dissociated from the hemoglobin and given to the tissues .As one oxygen dissociates it makes other oxygen to dissociate.

In alveoli the partial pressure of oxygen is high and it is fully saturated with hemoglobin.hemoglobin will pick up oxygen molecule and will become gully saturated with oxygen molecule.in tissue the partial pressure of oxygen would be low so unloading of oxygen molecule will take place and is taken up by tissues.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Which one of these is not an allosteric effector of hemoglobin binding to O2? a.CO which...

Which one of these is not an allosteric effector of hemoglobin binding to O2? a.CO which binds in the same spot as O2 b.2,3-BPG which binds in the middle of the tetramer c.CO2 which binds at the N-terminus of the subunits d.H+ which binds to the amino acid side chains disrupting IM forces

For hemoglobin and myoglobin, discuss the mechanism, similarities, differences, and effects of O2 binding on the...

For hemoglobin and myoglobin, discuss the mechanism, similarities, differences, and effects of O2 binding on the enzymes. What happens to the enzyme structure, and what do these structural changes then cause in terms of functional changes, if any? What role does BPG play for the enzyme and why would this be the case? What about H+? How does a baby breathe in the womb?

Describe the concept of cooperativity increase substrate binding affinity and provide an example.

what does cooperativity refer to within hemoglobin molecules?

Starting with deoxyhemoglobin, describe how the binding of one molecule of O2 to one of its...

Starting with deoxyhemoglobin, describe how the binding of one molecule of O2 to one of its heme groups affects the hemoglobin protein and its function. Also, describe the mechanisms by which CO2 and 2,3-BPG affect hemoglobin function and explain how these effects are important for the physiological functions of organisms that use hemoglobin for carrying oxygen.

What would happen to the O2-binding curve of hemoglobin when BPG is removed from its environment?...

What would happen to the O2-binding curve of hemoglobin when BPG is removed from its environment? A. The shape of the binding curve will not be affected. B. The sigmoid nature of the curve would diminish. C. The sigmoid nature of the curve would become more accentuated. D. Hemoglobin will not bind O2 any more.

List positive and negative effectors for oxygen binding to hemoglobin. explain cooperative binding using hemoglobin as...

List positive and negative effectors for oxygen binding to hemoglobin. explain cooperative binding using hemoglobin as an example. Correlate the NCI involved in stabilizing Hb’s and Mb’s structures. please answer all

Describe the relationship between the partial pressure of oxygen and the binding of oxygen to hemoglobin.

Mutations 1. Explain how a mutation in one of the hemoglobin subunit genes leads to symptoms...

Mutations 1. Explain how a mutation in one of the hemoglobin subunit genes leads to symptoms of low blood oxygen, fatigue, and clogged capillaries. In your explanation, include the effect of the mutation on the primary, tertiary, and quaternary levels of protein synthesis and connect the protein’s attributes to the sickle-shaped red blood cells. In your explanation, compare the mutant subunit to the normal subunit.

Describe the relationship between chemical equilibrium and the binding of hemoglobin to oxygen and explain why...

Describe the relationship between chemical equilibrium and the binding of hemoglobin to oxygen and explain why strong acids are good conductors of electricity and weak acid are not please help me and explain in detail so i can understand.( preferably give examples for both questions) thanks! :)

Subjects