Question
In: Nursing
A dose of 2 mg/kg of an antibiotic results in a peak blood serum level of...
A dose of 2 mg/kg of an antibiotic results in a peak blood serum level of 5 mcg/mL. How many milligrams of the drug should be given to a 143 lb patient if a peak blood serum level of 5.5 mcg/mL is desired? Round answer to the nearest whole number. Do not include units.
Solutions
Expert Solution
A dose of 2 mg/ kg of an antibiotic results in a peak blood serum level of 5mcg/mL.
Patients body weight :143lb
Converting weight from pounds (lb) to kilograms (kg):
1 lb = 0.454kg
143lb= 0.454 × 143
=64.922kg
After rounding off,
143lb =65kg
With the given information,
A dose of 2mg/kg of an antibiotic results in peak blood serum level of 5mcg/mL .
2mg/kg----------------------5mcg/mL
' 
' mg/kg-----------------5.5mcg/mL
By using Cross multiplication,
2 × 5.5
= --------------------------
5
11
= -----------------------
5
= 2.2mg/kg
Drug dose required for total body weight of the patient :
Total body weight of the patient is 65kg.
1kg ------------------2.2mg
For 65kg---------------------?
Cross multiplication,
= 65 × 2.2mg
= 143mg
Based on the given information,
In a patient having a body weight of 143lb,to attain a peak blood serum level of 5.5mcg/mL,the desired dose of drug is 143mg.
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