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A dose of 2 mg/kg of an antibiotic results in a peak blood serum level of...

A dose of 2 mg/kg of an antibiotic results in a peak blood serum level of 5 mcg/mL. How many milligrams of the drug should be given to a 143 lb patient if a peak blood serum level of 5.5 mcg/mL is desired? Round answer to the nearest whole number. Do not include units.

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Expert Solution

A dose of 2 mg/ kg of an antibiotic results in a peak blood serum level of 5mcg/mL.

Patients body weight :143lb

Converting weight from pounds (lb) to kilograms (kg):

1 lb = 0.454kg

143lb= 0.454 × 143

=64.922kg

After rounding off,

143lb =65kg

With the given information,

A dose of 2mg/kg of an antibiotic results in peak blood serum level of 5mcg/mL .

2mg/kg----------------------5mcg/mL

      

' ' mg/kg-----------------5.5mcg/mL

By using Cross multiplication,

2 × 5.5

= --------------------------

5

11

= -----------------------

5

= 2.2mg/kg

Drug dose required for total body weight of the patient :

Total body weight of the patient is 65kg.

1kg ------------------2.2mg

For 65kg---------------------?

Cross multiplication,

= 65 × 2.2mg

= 143mg

Based on the given information,

In a patient having a body weight of 143lb,to attain a peak blood serum level of 5.5mcg/mL,the desired dose of drug is 143mg.

Nightingale answered 1 year ago
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