Consider an individual that is homozygous for the short allele of the 5-HTT gene. 1) If...

Consider an individual that is homozygous for the short allele of the 5-HTT gene.

1) If this individual is exposed to relatively few stressful life events, how would you expect the probability of major depression to compare an individual that is homozygous for the long allele?

2) If this individual is exposed to many stressful life events, how would you expect the probability of major depression to compare an individual that is homozygous for the long allele?

Solutions

Expert Solution

1) If this individual is exposed to relatively few stressful life events, how would you expect the probability of major depression to compare an individual that is homozygous for the long allele?

According to the research carried out by Goldman et al., the individuals that have a short allele for 5HTT, will be more prone to be affected by any stressful traumatic event, to be inclined towards major depressive syndrome as compared to the individuals having a long arm. The greatest probability of being affected by the smallest stressful event is by individuals having S/S followed by individuals having an S/L genotype and the least is by individuals having the L/L genotype.

2) If this individual is exposed to many stressful life events, how would you expect the probability of major depression to compare an individual that is homozygous for the long allele?

If the individual has an S/S or S/L genotype, it has been reported that trauma has an even bad effect, as compared to those who do not have an S allele, I.e having L/L allele, p< 0.05.

Hayet Jeridi answered 1 year ago

Next > < Previous

Related Solutions

The Bombay phenotype occurs when an individual human is homozygous for a recessive allele at the...

The Bombay phenotype occurs when an individual human is homozygous for a recessive allele at the FUT1 locus. Individuals with this genotype do not make a precursor substance required to synthesize the A and B antigens that sometimes appear on human red blood cells. Regardless of their genotype at the ABO blood type locus, individuals who are homozygous for the Bombay phenotype allele at the FUT1 locus will appear to have blood type O on standard blood type tests. Note:...

Flies homozygous or hemizygous for the w1 allele of the white gene (Xw1/Xw1 or Xw1/Y) have...

Flies homozygous or hemizygous for the w1 allele of the white gene (Xw1/Xw1 or Xw1/Y) have white eyes, whereas flies homozygous or hemizygous for the wa allele of the white gene (Xwa/Xwaor Xwa/Y) have orange eyes. What is the dominance relationship between the w1 and the wa alleles, knowing that in the offspring of a cross between white-apricot females and white males the heterozygous females of the F1 generation (Xwa/ Xw1) have lighter orange eyes than homozygous Xwa/Xwa parental...

The normal chemokine receptor 5 gene (CCR5) allele “+” and a variant allele D was found...

The normal chemokine receptor 5 gene (CCR5) allele “+” and a variant allele D was found in a population of people. The variant D has a deletion of 32 base pairs called “Delta 32”. A sample of people from this population were tested for the variation in the CCR5 gene. The researchers found 16 people were homozygous for Delta 32; 165 people were heterozygous for the Delta 32 deletion; 433 people did not have the Delta 32 deletion. Choose all...

In Drosophila, the recessive dp allele of the dumpy gene produces short, curved wings, while the...

In Drosophila, the recessive dp allele of the dumpy gene produces short, curved wings, while the recessive allele bw of the brown gene causes brown eyes. In a testcross using females heterozygous for both of these genes, the following results were obtained: wild-type wings, wild-type eyes 178 wild-type wings, brown eyes 185 dumpy wings, wild-type eyes 172 dumpy wings, brown eyes 181 In a testcross using males heterozygous for both of these genes, a different set of results was obtained:...

Based on the Huntington disease which has the gene of HTT gene. Answer the following questions:...

Based on the Huntington disease which has the gene of HTT gene. Answer the following questions: 1a) Is the gene exonic or not?, 1b) what type of variant (SNP of CNV) and if the resultant changes in protein or protein level. 2) Is the variant found in the non-coding region and also is it involved in transcriptional regulation, if so describe the proposed pathway. 3) Draw a three-generation pedigree with at least 15 family members. 4) A narrative describing the pedigree...

Based on the Huntington disease which has the gene of HTT gene. Answer the following questions:...

Based on the Huntington disease which has the gene of HTT gene. Answer the following questions: 1)Description of genomic/epigenomic/cytogenetic/transcriptomic/proteomic characterization/detection of disease (how is the genetic cause determined) 2) Give a flow chart for determination of the genetic cause at the clinical level (i.e. phenomic upon the first presentation to the clinic to confirmation of genetic disorder).

calculating allele frequencies in a gene pool

In the beetles described in the animation, there were two alleles for color, brown and green. Suppose that you discover a very small population of these beetles, consisting of the individuals shown below. How can you calculate the frequency of each allele in this population? 1) to calculate the frequency of brown allele, count the number of ___ and divide by the total number of alleles in this population. 2) In this beetle population the number of brown alleles is...

Develop a case study/report on the Huntington disease and the gene for this disease is HTT...

Develop a case study/report on the Huntington disease and the gene for this disease is HTT gene. When you are developing the case study, start it from the DNA variant(a specific variant of the HTT gene) to the phenotype of the diseased patient. The case report you should include the following: 1) the Genomic coordinates of the variant of the disease. 2) Transcript level coordinates of the variant if within mRNA (immature or mature) 2a) 5’-UTR, 3’, intron, exon, or...

Develop a case study/report on the Huntington disease and the gene for this disease is HTT...

Develop a case study/report on the Huntington disease and the gene for this disease is HTT gene. When you are developing the case study, start it from the DNA variant(a specific variant of the HTT gene) to the phenotype of the diseased patient. The case report you should include the following: 1) If the gene exonic, type of variant (SNP of CNV) and resultant changes in protein or protein level. 2) Is the variant found in the non-coding region and...

Develop a case study/report on the Huntington disease and the gene for this disease is HTT...

Develop a case study/report on the Huntington disease and the gene for this disease is HTT gene. When you are developing the case study, start it from the DNA variant(a specific variant of the HTT gene) to the phenotype of the diseased patient. The case report you should include the following: . 1a) Transcript level coordinates of the variant if within mRNA (immature or mature) 1b) 5’-UTR, 3’, intron, exon, or splice site as examples 2c) If exonic, type of...

Subjects