Question

Describe the properties of an amphipathic alpha helix and identify numbered amino acids in a dodecamer polypeptide that contribute to the chemical properties of this secondary protein structure. Where are amphipathic alpha helices found in a globular cytosolic protein?

Answer 1

Ans-)It is a secondary structure- of protein in which one side of Amino acid is hydrophilic whereas other side is hydrophobic. In each residue, the pattern of Amino acid alters . It is important for the interaction of membrane with proteins and peptides.

The membrane made up of different types of membrane Proteins. Lipid bilayer membrane is made up of it's Mass. The hydrophobic side of amphiphatic helix interacts with hydrophobic tail of lipid in the inner side of bilayer whereas hydrophilic end is exposed to water.

Amphiphatic alpha helix are present at the surface of globular cystolic protein.