Question

1.) Which of the the following is a highly sulphated glycosaminoglycan that can act as an anticoagulant?

A) Heparin

B) Hyaluronic acid

C) Lectin

D) Glycosaminoglycans

E) Ceramides

2.) Which of the following is a protein that forms transmembrane pores allowing a growing polypeptide

chain to pass through the RER membrane?

A) Docking protein

B) Lysosomal protein

C) Signal recognition particle

D) Translocon

E) Signal peptide

3.) Which of the following linkages are found at branching points a glycogen molecule?

A) alpha 1,4 linkages between glucose units

B) beta 1,4 linkages between glucose units

C) beta 1,6 linkages between glucose units

D) alpha 1,6 linkages between glucose units

E) alternating alpha 1,4 and beta 1,4 linkages between glucose units

Answer 1

1) The correct option is A) Heparin.

                    Heparin is a highly sulphated glycosaminoglycan which can act as an anticoagulant. It is found and stored in secretory granules of mast cells. Heparin is highly negatively charged and acts as electrostatically preserver . Heparin acts as an anticoagulant and it is also the first line choice for thromboembolic diseases. Heparan sulfate has numerous biological activities and functions, which includes cell adhesion, regulation of cell growth and proliferation, developmental processes, cell surface binding of lipoprotein lipase and other proteins, angiogenesis.

2) The correct option is D) Translocon.

                         The protein which forms a transmembrane pore that permits preproteins to pass through the ER membrane is called the translocon. The translocon is a complex of proteins associated with the translocation of polypeptides across membranes. It can also translocate and integrate membrane proteins in the correct orientation into the membrane of the endoplasmic reticulum.

3) The correct option is A) alpha 1,4 linkages between glucose units.

                            Glycogen is a branched biopolymer, which consists of linear chains of glucose residues with further chains branching off every 8 to 12 glucoses . Glucoses linked together linearly by α(1→4)glycosidic bonds from one glucose to the next glucose.