Question

A hospital pharmacist prepares an intravenous solution containing 300 mg of DRUG X in 250 mL normal saline. The infusion rate of DRUG X is 15 mcg/kg/min, and this solution is to be administered to a patient weighing 132 pounds. What would be the appropriate infusion rate of the solution for this patient in mL/hr? The rate is _______ mL/hr.

Answer 1

* Infusion rate=15 mcg/ kg/ minute. * Weight= 132 lb= 59.874 kg ,so infusion rate= 15 mcg× 59.874 kg=898.05 mcg/ minute. * Total fluid volume= 250 ml, Drug dose= 300 mg. * Infusion Rate in ml/ hr=250 ml/300 mg× 1 mg/1000 mcg×898.05 kg/ 1 minute×60/1 hr =898.05/20=44.90 ml/ hr= 45 ml/ hr