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AMP is synthesized in a two-step reaction sequence involving inosinic acid, ATP and glutamine. Group of...

AMP is synthesized in a two-step reaction sequence involving inosinic acid, ATP and glutamine.

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False

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Question 801 pts

During starvation when gluconeogenesis increases to maintain the levels of blood glucose, the metabolism of glutamate to glucose-6-phosphate is enhanced.

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True

False

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Question 811 pts

Measurement of blood ammonia level is a sensitive test of kidney function.

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False

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Question 821 pts

The increase of glycogenolysis in muscle produced by epinephrine may be attributed to the conversion of phosphorylase b to phosphorylase a.

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True

False

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Question 831 pts

Glucagon targets primarily on liver to increase glycogen degradation.

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True

False

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Question 841 pts

The formation of glucose 6-phosphate renders the entry of glucose into most cells almost irreversible (i.e. staying intracellular).

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True

False

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Question 851 pts

Before fatty acids can be oxidized, they must be activated for reactions. This activation process is catalyzed by acyl carrier protein.

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True

False

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Question 861 pts

In the oxidation of fatty acids, transportation of activated fatty acids into mitochondria requires the reaction with carnitine.

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True

False

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Question 871 pts

The breakdown of the fatty acid CH3CH2CH2CH2CH2CH2CH2CH2COOH via the β-oxidation pathway would yield three moles acetyl units and one mole propionyl unit.

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True

False

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Question 881 pts

In the biosynthesis of fatty acid, the acyl group carrier for the biosynthetic reaction is acyl carrier protein.

Group of answer choices

True

False

Solutions

Expert Solution

1. AMP is synthesized in a two-step reaction sequence involving inosinic acid, ATP and glutamine. True.

2. During starvation when gluconeogenesis increases to maintain the levels of blood glucose, the metabolism of glutamate to glucose-6-phosphate is enhanced. True.

Glutamate derived from glycogenic amino acids and converted to glutamate to glucose-6-phosphate via gluconeogeneic pathway.

3. Measurement of blood ammonia level is a sensitive test of kidney function. True.

4. The increase of glycogenolysis in muscle produced by epinephrine may be attributed to the conversion of phosphorylase b to phosphorylase a. True.

Epinephrine enhance the protein kinase mediated cascade which convert phosphorylase b to phosphorylase a.

5. Glucagon targets primarily on liver to increase glycogen degradation. True.

Glucagon targets primarily on liver to increase glycogenolysis (degradation pathway of glycogen).

6. The formation of glucose 6-phosphate renders the entry of glucose into most cells almost irreversible (i.e. staying intracellular). True

The formation of glucose 6-phosphate renders the entry of glucose into most cells almost irreversible because of the hydrolysis of pyrophosphate (PPi) by the enzyme pyrophosphatase.

7. Before fatty acids can be oxidized, they must be activated for reactions. This activation process is catalyzed by acyl carrier protein. True

8. In the oxidation of fatty acids, transportation of activated fatty acids into mitochondria requires the reaction with carnitine. True

Carnitine is responsible for the transport of activated fatty acids from cytosol to mitochondria.

9. The breakdown of the fatty acid CH3CH2CH2CH2CH2CH2CH2CH2COOH via the β-oxidation pathway would yield three moles acetyl units and one mole propionyl unit. True

10. In the biosynthesis of fatty acid, the acyl group carrier for the biosynthetic reaction is acyl carrier protein. True.

The acyl carrier protein (ACP) is acta as a cargo from active site to active site.


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