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Questions are applied for the following drugs: prazosin, atenolol, labetalol, celiprolol. clonidine Molecular target(s) of the...

Questions are applied for the following drugs: prazosin, atenolol, labetalol, celiprolol. clonidine

Molecular target(s) of the drug?

Is the drug a receptor agonist? If yes, what receptor(s)?

Is the drug a receptor antagonist? If yes, what receptor(s)

Does the drug cause vascular smooth muscle contraction or relaxation?

Will the drug inhibit a vascular smooth muscle contraction induced by phenylephrine?

If yes, the action via which one of the following three mechanisms:

(1) the drug inhibits the binding of phenylephrine to its receptor; OR

(2) the drug inhibits the signal transduction induced by phenylephrine; OR

(3) the drug causes vasodilation.

Will the drug inhibit a vascular smooth muscle contraction induced by angiotensin II?

If yes, the action via which one of the following three mechanisms:

(1) the drug inhibits the binding of angiotensin II to its receptor; OR

(2) the drug inhibits the signal transduction induced by angiotensin II; OR

(3) the drug causes vasodilation.

Solutions

Expert Solution

Drug-Prazosin


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