In: Nursing
Questions are applied for the following drugs: prazosin, atenolol, labetalol, celiprolol. clonidine
Molecular target(s) of the drug?
Is the drug a receptor agonist? If yes, what receptor(s)?
Is the drug a receptor antagonist? If yes, what receptor(s)
Does the drug cause vascular smooth muscle contraction or relaxation?
Will the drug inhibit a vascular smooth muscle contraction induced by phenylephrine?
If yes, the action via which one of the following three mechanisms:
(1) the drug inhibits the binding of phenylephrine to its receptor; OR
(2) the drug inhibits the signal transduction induced by phenylephrine; OR
(3) the drug causes vasodilation.
Will the drug inhibit a vascular smooth muscle contraction induced by angiotensin II?
If yes, the action via which one of the following three mechanisms:
(1) the drug inhibits the binding of angiotensin II to its receptor; OR
(2) the drug inhibits the signal transduction induced by angiotensin II; OR
(3) the drug causes vasodilation.