In many animal cells, the uptake of glucose into the cell occurs by a cotransport mechanism, in which glucose is cotransported with Na^+ ions.

In many animal cells, the uptake of glucose into the cell occurs by a cotransport mechanism, in which glucose is cotransported with Na⁺ ions.

Complete the diagram below using the following steps.

Drag the pink labels to the pink targets, indicating the relative concentration at glucose inside and outside the cell.
Drag the correct white target to the white target, indicating the direction that Na⁺ ions and glucose move through the cotransporter
Drag the blue labels to complete the sentences on the right, indicating how Na⁺ ions and glucose move through the cotransporter relative to their electrochemical and concentration gradients.

Solutions

Expert Solution

The sodium-glucose-linked transporter (SGLTs, a co-transporter) uses the ATPase pump's energy through the downhill sodium ion gradient for glucose transportation across the apical membrane (against the glucose gradient). SGLTs are an example of secondary active transport. The glucose transporters (GLUT) present in the basolateral membrane now allow the glucose transport into the peritubular capillaries. Inhibition of the Na+/K+/ATPase fails to generate the energy required for the SGLT secondary transporters, inhibiting glucose uptake.

Sugars such as glucose, galactose into the microvilli epithelial cells are based on sodium mediated cotransport, whereas fructose cannot be transported by sodium mediated transport during absorption after digestion. H+ mediated oligopeptide transport is present in the gut epithelium.

Dr. OWL answered 3 years ago

Next > < Previous

Related Solutions

Cholera toxin inhibits the Na+/K+ATPase activity of intestinal epithelial cells. Resulting with decreased uptake of glucose....

Cholera toxin inhibits the Na+/K+ATPase activity of intestinal epithelial cells. Resulting with decreased uptake of glucose. Describe why inhibiting the Na/K+ ATPase pump affects glucose uptake in the intestine.

Animal cells generally have a higher concentration of Na+ outside of the cell than inside the...

Animal cells generally have a higher concentration of Na+ outside of the cell than inside the cell and a membrane potential around -70 mV. When an Na+ moves into an animal cell, how does that movement impact the membrane potential? How does that movement impact the Na+ concentration gradient? Explain what an equilibrium potential for an ion is, what the resting membrane potential is, and how they are different.

How the concentration polarization occurs in galvanic and electrolylic cells (in details) mechanism of each cell

Comparing plant cells and animal cells Plant cells and animal cells share many of the same structures, but each type of cell also has unique structures.

Part A - Comparing plant cells and animal cells Plant cells and animal cells share many of the same structures, but each type of cell also has unique structures. In this activity, you will indicate which cell structures are found only in plant cells, only in animal cells, or in both plant and animal cells. Drag each cell structure to the appropriate bin. If a structure is found in both plant cells and animal cells, drag it to the "both"...

Which of the following viral types enter animal cells via fusion with the animal cell membrane?...

Which of the following viral types enter animal cells via fusion with the animal cell membrane? Multiple Choice enveloped viruses non enveloped viruses naked viruses All of these choices are correct.

Which of the following correctly depicts the mechanism of the Na+/glucose co-transporter discussed in class? Select...

Which of the following correctly depicts the mechanism of the Na+/glucose co-transporter discussed in class? Select one: a)Both the Na and the glucose must bind which allows Na to move against its gradient because glucose is moving down its gradient. b)Glucose is pushed against its gradient because Na will be moving with its electrochemical gradient. c)This transporter binds Na on the outside of the cell, then ATP adds on a Phosphate, which changes the confirmation and open to cells interior...

The Na –glucose symport system of intestinal epithelial cells couples the \"downhill\" transport of two Na...

The Na –glucose symport system of intestinal epithelial cells couples the \"downhill\" transport of two Na ions into the cell to the \"uphill\" transport of glucose, pumping glucose into the cell against its concentration gradient. If the Na concentration outside the cell ([Na ]out) is 163 mM and that inside the cell ([Na ]in) is 23.0 mM, and the cell potential is -51.0 mV (inside negative), calculate the maximum ratio of [glucose]in to [glucose]out that could theoretically be produced if...

The Na –glucose symport system of intestinal epithelial cells couples the \"downhill\" transport of two Na...

The Na –glucose symport system of intestinal epithelial cells couples the \"downhill\" transport of two Na ions into the cell to the \"uphill\" transport of glucose, pumping glucose into the cell against its concentration gradient. If the Na concentration outside the cell ([Na ]out) is 153 mM and that inside the cell ([Na ]in) is 19.0 mM, and the cell potential is -49.0 mV (inside negative), calculate the maximum ratio of [glucose]in to [glucose]out that could theoretically be produced if...

Epithelial cells of the intestine contain a transport protein, the sodium/glucose symporter, that allows for uptake...

Epithelial cells of the intestine contain a transport protein, the sodium/glucose symporter, that allows for uptake of glucose from the intestinal lumen not the epithelial cells. Is this an active or passive transporter, and if active, what is the energy source for the transport and therefore the classification of this protein? What other protein needs to be present and active for the sodium/glucose symporter to work, and why?

Na+ enters nerve cells through a channel in the cell membrane when the cell is stimulated....

Na+ enters nerve cells through a channel in the cell membrane when the cell is stimulated. What would happen to the rate of Na+ entry if you increased the concentration of Na+ outside the cell while not changing the internal concentration? A. No change B. Increase C. Decrease A scientist has added a colored molecule to the exposed portion of transmembrane proteins in a small patch on the exterior leaflet (exterior surface) of a membrane. She comes back after a...

Subjects