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A 33 year old female is being treated for rheumatoid arthritis with Methotrexate, a Disease-Modifying Antirheumatic...

A 33 year old female is being treated for rheumatoid arthritis with Methotrexate, a Disease-Modifying Antirheumatic arthritis drug (DMARD). She has a history of DVT, but no other significant medical history. The physician currently increased her dose from 10 mg/week to 25 mg/week and also added Leucovorin to her treatment regimen. Bone marrow suppression is a common adverse effect of methotrexate treatment.

What are contraindications for treatment with a DMARD?

What therapeutic effects should the patient experience from treatment with a DMARD?

Why has the physician ordered Leucovorin (See Chapter 45-Methotrexate)? Explain your answer.

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Expert Solution

Therapeutic effects of DMARD in rheumatoid arthritis and its contraindications are written in white paper and submitted along with this written content. Please go through the handwritten answers

Nightingale answered 2 years ago
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