A lagging strand forms by joining Okazaki fragments joining leading strands breaking up a leading strand...

A lagging strand forms by

joining Okazaki fragments

joining leading strands

breaking up a leading strand

joining primers, Okazaki fragments, and leading strands

joining primers

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Expert Solution

Ans: A DNA helix has two strands at replication fork,(The site of DNA replication where two replicating single strands seperates)one is a Leading strand and another one is Lagging strand.

The Lagging strand & leading strands forms as a result of DNA replication process.The process starts when an enzyme named Halicase unwinds the double strand DNA.Another enzyme named Primase generates short strand of RNA that binds to the single stranded DNA to intiate DNA synthesis by DNA plymerase.This enzyme can work only in 5' (phosphate group) to 3'(hydroxyl group) direction so it replicates the leading strand continuously. Replication of Lagging strand is discontinuous with short okazaki's fragments being formed and later link together.

Okazaki's fragments are formed by joining of RNA primers & a specific group of RNA primers are called as Okazaki's fragment.

Thus it is concluded that a lagging strand is formed by joining Okazaki fragments.

gladiator answered 1 year ago

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