Question

What are macrophages? Where do they come from? What is the role of the macrophage in the immune reaction?

Answer 1

Ans- Macrophages are phagocytes derived from blood monocytes. Monocytes that migrate into tissue in response to infection can differentiate into specific tissue macrophages. The mononcyte is a small, spherical cell with few projection , abundant cytoplasm and granules. Following migration of monocytes from the blood to various tissue,they undergo further differentiation into a variety of histological forms and all of which play a role in phagocytes including kuffer cells in the liver , alveolar macrophages. In the lung splenic macrophages, in the white pulp peritoneal macrophages,

Role of Macrophages-- Macrophages are multifunctional cells.

1} Macrophages are very malleable and take varied function in the growth and spread of cancer.

2} Macrophages are responsible for identifying, destroying and removed all foreign substance from the our body.

3} Macrophages are removal of cellular necrotic debris and tissue destruction.

4} Macrophages is restored, tissue repair is accelerated, creat feed-forward loop that restored homeostasis,,