Question

Examin the following lipid panel and answere the questions.

Lipid Profile	Patient Result	Reference Range
Cholesterol	305	<200 mg/dL
HDL Cholesterol	45	29-75 mg/dL
Tryglycerides	390	<250 mg/dL

1. Given the above information, what is Mike’s LDL cholesterol? Based on his LDLC, is he at high risk for coronary heart disease, moderate risk, or within the recommended range?

2. If Mike’s triglycerides were 450 mg/dL, could the LDL be calculated? Why or why not?

2. a) What would be the next step?

3. List eight risk factors associated with CHD as determined by the National Cholesterol Education Program (NCEP) Adult Treatment Panel.

4. How many risk factors does Mike presently have, given the information provided? Is he at high risk for CHD?

5. What are the follow-up testing and treatment recommendations by the NCEP Adult treatment panel?

6. List at least three types of drugs used to treat this condition and their affect (how they work and what they lower or decrease).

Answer 1

Examine the following lipid panel and answer the questions.

Lipid Profile	Patient Result	Reference Range
Cholesterol	305	<200 mg/dL
HDL Cholesterol	45	29-75 mg/dL
Tryglycerides	390	<250 mg/dL

1. Given the above information, what is Mike’s LDL cholesterol? Based on his LDLC, is he at high risk for coronary heart disease, moderate risk, or within the recommended range?

Answer: Mike LDL level 182 mg/dL and the Pt is very high risk for CAD

2. If Mike’s triglycerides were 450 mg/dL, could the LDL be calculated? Why or why not?

LDL = total cholesterol – HDL – TG/5

= 305- 45-450/5

= 305-45-90

= 305-135

=170 mg/dL

3. List eight risk factors associated with CHD as determined by the National Cholesterol Education Program (NCEP) Adult Treatment Panel.

• Cigarette smoking
• Hypertension (BP >140/90 mmHg or on antihypertensive medication)
• Low HDL cholesterol
• Men > 45 years; women >55 years
• Diabetes Mellitus
• Family History
• Sedentary life styles

4. How many risk factors does Mike presently have, given the information provided? Is he at high risk for CHD?

Answer: He is having more than 2 risk factors, so he is at High risk for CAD

5. What are the follow-up testing and treatment recommendations by the NCEP Adult treatment panel?

• TLC Diet
• Weight management
• Increased physical activity
• Drug therapy

6. List at least three types of drugs used to treat this condition and their affect (how they work and what they lower or decrease).

• HMG CoA reductase inhibitors (statins)
• Bile acid sequestrants
• Nicotinic acid

All medication used to decrease cholesterol levels in the blood