Explain the general mechanism for the simultaneous transport
of Na+ and K+ by the Na+/K+ ATPase (aka. Na+/K+ pump)
describing:
The result of this transport on the concentrations of Na+ and
K+ inside and outside of the cell
How the binding of Na+ and K+ are related to the conformation
changes on the protein
We discussed F-type pumps, which can also function in the
reverse direction (i.e. ATP synthase). Explain how this protein can
function both as a pump and...
Consider the following species: Na, Mg, Cl^-1,S,Cl,Ar,Na^+
(a) Order the above species in order of increasing atomic/ionic
radius.
(b) Order the above species in order of increasing electron
affinity
How would you explain fluid and electrolyte imbalances with Na+,
K+, Mag+, Cl-, Ca+, P? And what would the signs and symptoms be if
a person were to be hypo or hyper? And what would be the nursing
interventions? (Not sure if you know, but I thought I would ask
just in case.)
Thank you
Furosemide: Relative to normal, what would happen if the
drug furosemide inhibits
Na+/K+ and
Na+/Cl-
symport channels in the thick segment of the ascending limb
of the nephron tubule? Explain your reasoning for
each.
What would happen to water loss from the descending
limb? Why.
What would happen to the osmolarity of the filtrate
inside the bottom of the nephron loop? Why?
What would happen to the loss of salt (NaCl) from the
thin segment of the ascending limb. Why?
The initial concentrations of Na+ and Cl− in the reaction below
are each 0.0843 M. If the initial concentration of NaCl is 0 M and
the equilibrium constant is Kc=8.21 under certain conditions, what
is the equilibrium concentration of Na+?
NaCl(aq)⇌Na+(aq)+Cl−(aq)
Which of the following correctly depicts the mechanism of the
Na+/glucose co-transporter discussed in class?
Select one:
a)Both the Na and the glucose must bind which allows Na to move
against its gradient because glucose is moving down its
gradient.
b)Glucose is pushed against its gradient because Na will be
moving with its electrochemical gradient.
c)This transporter binds Na on the outside of the cell, then ATP
adds on a Phosphate, which changes the confirmation and open to
cells interior...
The
Goldman Equation
K+, Na+
and Cl- ions concentrations
Changing the ratio of one of the ions has
the most dramatic effect. Which is it? Why do you suppose this
is?