Question

In: Anatomy and Physiology

Which of the following occurs in photoreceptors when they are exposed to the appropriate wavelength of...

Which of the following occurs in photoreceptors when they are exposed to the appropriate wavelength of light?

Opsin and all-trans retinal combine to form rhodopsin.

PDE enzyme is activated, which increases cGMP levels.

Light-gated Na+ channels open, which depolarizes the cell.

cGMP levels decrease, which closes Na+ channels and hyperpolarizes the cell.

Solutions

Expert Solution

Answer )

a) Opsin and all -trans retinal combine to form rhodopsin.

Others are Incorrect .

Phototransduction mechanism

1)First when light falls it enters Cornea and then through Lens it reaches the Retina and retinal layers .

2)Retina has rods and cones .Rods for dark vision and cones for Colour vision .

3)Now a derivative of Vitamin A,11 cis retinal combine with Opsin to form rhodopsin,pigment in rod cells that is necessary for Vision .

4)After formation of All trans retinal ,transducin get activated by releasing GDP and get converted into activated Transducin with GTP .

5)Activated transducin activate Phosphodiesterases enzyme which is responsibe for degradation of Cyclic GMP .

6)Cyclic GMP is responsible for opened Na+ Channels .

7) Separated opsin produces these reactions timately leads to close some of the Na+ channels, and the result is a hyperpolarizing receptor potential.

8)The action potentials are transmitted to the brain.


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