The drug erythromycin has been proposed to lower the risk of premature delivery. However, there are...

The drug erythromycin has been proposed to lower the risk of premature
delivery. However, there are possible side effect of nausea when the drug is taken during pregnancy.
We want to estimate the incidence rate ?? of nausea during pregnancy, and we collect the 100 women
sample who are taking erythromycin regularly during weeks 24 and 28 of pregnancy, 90 of them
complained of nausea.
(a) [2 Points] Based on the sample, calculate the value of the point estimator of incidence rate ??.
(b) [4 Points] Please construct a 97% Confidence Interval for the incidence rate ??.
(c) [4 Points] Is (0.8415,0.9786) also a 97% confidence interval for the incidence rate ?? or Will
(0.8415,0.9786) have 97% contain the unknown true incidence rate ??? Why?
(d) [4 Points] Compare the confidence interval in Part (b) and Part (c), what’s the difference between
these two confidence intervals? Why we commonly use Symmetry setting in confidence interval?
Suppose that 75% of typical pregnant women (without taking erythromycin) complain of nausea
between weeks 24 and 28 of pregnancy.
(e) [4 Points] Test the hypothesis that the incidence rate ?? of nausea for the erythromycin group is
higher than the incidence rate for a typical pregnant woman at α = 5%.
(f) [5 Points] For reconfirm the result, we collect a new sample of 10 women during weeks 24 and 28
of pregnancy and find that all of them complain of nausea. Test the hypothesis that the incidence
rate ?? of nausea for the erythromycin group is higher than the incidence rate for a typical pregnant
woman based on the new sample at α = 5%. Hints: Use exact method and calculate its p-value.

Solutions

Expert Solution

orchestra answered 1 year ago

Next > < Previous

Related Solutions

A new drug is proposed to lower total cholesterol and a study is designed to evaluate...

A new drug is proposed to lower total cholesterol and a study is designed to evaluate the efficacy of the drug in lowering cholesterol. Fifteen patients agree to participate in the study and each is asked to take the new drug for 6 weeks. However, before starting the treatment, each patient's total cholesterol level is measured. The initial measurement is a pre-treatment or baseline value. After taking the drug for 6 weeks, each patient's total cholesterol level is measured again...

Yes, medical treatment has made astounding advances over the years. However, the packaging and delivery of...

Yes, medical treatment has made astounding advances over the years. However, the packaging and delivery of that treatment is often inefficient, ineffective, and consumer unfriendly. These problems beg for innovative solutions, so why is innovation so unsuccessful in health care?

A new drug has been developed to treat a condition, and it is alleged to be...

A new drug has been developed to treat a condition, and it is alleged to be more effective than traditional treatment. An experiment will be conducted to test whether the claim is true. To perform the hypothesis test, a 99% confidence level is selected for the hypothesis test. The new drug will be administered to a sample of 200 individuals with the condition, selected at random. Another 300 individuals are randomly selected to receive the traditional treatment. Of the 200...

cisplatin(or cis- diamminedichloroplatinum(II) is an anticancer drug. The trans isomer, however has no effect. how does...

cisplatin(or cis- diamminedichloroplatinum(II) is an anticancer drug. The trans isomer, however has no effect. how does cisplatin funtion to kill tumors?

1.The TCA cycle in a particular tissue has been inhibited by fluoroacetate. However, it is not...

1.The TCA cycle in a particular tissue has been inhibited by fluoroacetate. However, it is not the fluoroacetate that is responsible for the inhibition. It gets converted to another molecule that enters the TCA cycle and is transformed into the inhibitor. a) Propose the inhibitor molecule and mechanistically show the conversion of fluoroacetate to the inhibitor. b) Indicate at what step fluoroacetate ultimately inhibits the TCA cycle. c) Explain why you think fluoroacetate acts as an inhibitor of this enzyme?...

It has been proposed that lightning be harvested for energy. Measurements of lightning strikes indicate that...

It has been proposed that lightning be harvested for energy. Measurements of lightning strikes indicate that they have the following average properties (note, these are reasonable approximations): Potential difference between each end of 100 million V Current of 30000 A Time of 1.67E-4 seconds 20 strikes per square kilometer per year in lightning prone regions of the United States and 200 strikes per square kilometer per year in the most lightning prone regions in the world (Congo). "Lightning collectors" are...

Exercise 2: A new IS project has been proposed that is expected to produce not only...

Exercise 2: A new IS project has been proposed that is expected to produce not only cost savings but also an increase in revenue. The initial capital cost to establish the system is estimated to be $500,000. The remaining cash flow data is presented in Table 2.10. Using a spreadsheet program, calculate the payback period, internal rate of return, and net present value for this project. Assume that the cost of capital is 7% and the effective tax rate is...

The following mechanism has been proposed for this catalyzed reaction: H2O2 + I– → IO– +...

The following mechanism has been proposed for this catalyzed reaction: H2O2 + I– → IO– + H2O H2O2 + IO– → I– + H2O + O2 a) Write the formula for any intermediate. b) Write the formula for any catalyst. c) Show how the steps in the mechanism add to the decomposition of H2O2.

Use of methanol has been proposed to rid a wastewater of nitrate by biological denitrification to...

Use of methanol has been proposed to rid a wastewater of nitrate by biological denitrification to N2. (a) Write a balanced overall equation for nitrate removal with methanol, using fs=0.36 and assuming nitrate serves as the nutrient source for bacteria. (b) If the nitrate concentration in the wastewater equals 100mg/l, what concentration of methanol must be added for complete nitrate removal? (c) What percentage of the nitrate-nitrogen is used for cell synthesis? please let me know the process

A new design for the braking system on a certain type of car has been proposed....

A new design for the braking system on a certain type of car has been proposed. For the current system, the true average braking distance at 40 mph under specified conditions is known to be 120 ft. It is proposed that the new design be implemented only if sample data strongly indicates a reduction in true average braking distance for the new design. (a) Define the parameter of interest. μ = true average braking distance for the new design μ...

Subjects