How is the electron transport chain tied to the synthesis of nucleoside triphosphates?

Expert Solution

In mitochondria, by the process of oxidative phosphorylation ATP synthesis tanes place.

Oxidative phosphorylation involve both oxidation and phosphorylation ( ADP+ pi= ATP).

During the metabolic process released energy is captured in form of NADH and FADH2. These reducing equivalents enter in to ETC. In ETC, electron from NADH and FADH2 is transferred in to electron transport chain. Suring transport of electrons at some complexs enough energy is released ( complex I, III, , IV) . This energy is used to transport proton from mitochondrial matrix to intermembrane space. Due to transport of H+ in to intermembrane space. There is generation of proton motive force ( PMF) due to accumulated H+. As these H+ enter in to mitochondria matrix using F0 subunit of fifth complex, energy is released which is used to syntesis of ATP by F 1 subunit. So this proton gradient act as immediate energy source for generation of ATP.

The process of ETC showing synthesis of ATP has been attached below.

gladiator answered 2 years ago

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How is the electron transport chain tied to the synthesis of nucleoside triphosphates?

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