Question

Elaborate on the difference between primary and secondary Parkinson's disease

Answer 1

#. Parkinson Disease :-

Is a degenerative disorder of the basal ganglia (corpus striatum) involving the dopaminergic nigrostriatal pathway producing a syndrome of abnormal movement called parkinsonism.

Parkinson classification :-

Primary or idiopathic Parkinson disease - loss of pigmented neurons in the substantia nigra

Secondary parkinsonism- due to trauma, infection, neoplasm, atherosclerosis, toxins, drug intoxication

Secondary form of Parkinson :-

Drug-induced parkinsonism caused by neuroleptics, antiemetics, and antihypertensives is the most common cause of the secondary form and is usually reversible.