In: Biology
Which of the following is NOT a checkpoint?
a. S-G2 b. G2-M c.metaphase araphase d.G1-S
S-G2 is NOT a checkpoint among all other options.
Why G2-M is a checkpoint
After the cell performs DNA replication during S or synthesis phase, it undergoes a growth phase that is known as G2 phase. It is in this phase, the cell prepares the required mitotic proteins and ensures the cell's status to be perfect to enter the proliferative mitotic phase or M phase. Cyclin-CDKs act as a common uniting factor in the transition of the cell from G2 to S.
Why Metaphase-Anaphase is a checkpoint
It is also known as spindle checkpoint. It is in this phase that the cell prevents the separation of duplicated chromosomes until each chromosome is attached to the spindle fibers.
Why G1-S is a checkpoint
G1 checkpoint is the phase in which the cell prepares to be committed to enter the cell cycle. Depending on the internal and external conditions, the cell decides whether it can delay in G1 phase or it'll go to Go phase.