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medications in the sodium channnel blockers include? select all that apply Carbamazepine,phenytoin, vigabatrin, lamotrigin

medications in the sodium channnel blockers include? select all that apply

Carbamazepine,phenytoin, vigabatrin, lamotrigin

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Expert Solution

Sodium channel blockers are drugs which impair the conduction of sodium ions through sodium channels, the sodium channel blockers achieves delayed depolarization because sodium stays out, and membrane stabilization, the main uses of the sodium channel blockers are local anesthetics, anti arrhythmic, anti epileptics,the medication in the sodium channel blockers include : a) amiloride:it is an epithelial sodium channel blocker used in the hypokalaemia induced by loop diuretics, b)spironolactone:it is aldosterone receptor antagonist, c)tetrodotoxin: it is a sodium channel blocker,d) phenytoin: it is a anti arrhythmic drug( sodium channel blocker) it inhibitis sodium channel opening in neurons therefore shorten action potential duration , it is used in seizures, prevention of fibrillation, ventricular arrhythmias and infractions. e) procainamide : it is a class 1A antiarrhythmic drug ( sodium channel blocker) , it is a systemic anaesthetic, f)quinidine : it is class 1A antiarrhythmic drug ( sodium channel blocker) used in supraventicular and ventricular arrhythmias, g)lidocaine:it is sodium channel blockers it is used as local anesthetic h) xilocaine: it is a sodium channel blocker it is a local anesthetic, i) carbamazepine: it is a sodium channel inhibitor: it is used is anti convulsant, seizures, migraines, bipolar associated mania,j) L amotrigine: it is a member of sodium channel blockers class of antiepileptic drugs, it is an anticonvlsant medication used to treat epilepsy and bipolar disorder, the carbamazepine, phenytoin, lamotrigin are sodium channel blockers, but vigabatrin is a antiepiletic drug that acts by elevating brain GABA levels.


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