Question

In: Nursing

A key concern in urea cycle disorders is the toxic accumulation of: ammonia. homocysteine. isovaleric acid....

A key concern in urea cycle disorders is the toxic accumulation of:

ammonia.

homocysteine.

isovaleric acid.

phenylalanine.

Solutions

Expert Solution

A key concern in Urea cycle disorders is the toxic accumulation of:

Answer : Ammonia ( first option)

Urea cycle disorders are a group of inherited disorders characterised by lack of one or more enzymes, that helps in the breakdown of nitrogenous products, end prroducts of protein metabolism, resulting in accumulation of nitrogenous wastes , especially Ammonia. Along with ammonia , glutamine and Alanine also may get accumulated.

Other options: ( are wrong options)

Homocysteine: It is an Aminoacid . It is not a nitrogenous waste. Homocysteine is a homologue of cysteine, amino acid.

Isovaleric acid: It is a natural fatty acid with pungent smell, found in a wide variety of plants and essential oil, whose volatile esters are used in perfumery.

Phenylalanine : An essential amino acid gound in most of the animal protein. It is essential for growth. The inability to metabolize it leads to phenylketonurea.


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