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What are the implications of the existence of polysomes, which are clusters of ribosomes attached to...

What are the implications of the existence of polysomes, which are clusters of ribosomes attached to RNA, which relay some DNA information for cell reproduction. Discuss

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  • Polysomes, also known as polyribosomes or ergasomes, are ribosomes groups that are attached to a molecule of mRNA.
  • It includes an mRNA molecule complex in association with some ribosomes translating instructions of mRNA into polypeptides.
  • These are produced in the elongation phase of protein synthesis during production of elongated polypeptides.
  • Structure of polysomes vary between prokaryotes and eukaryotes and also different kind of polysomal structures are formed by different cells.
  • Identification of polysome type may reveal the identity of cells i.e. whether it is prokaryotic cell or eukaryotic cell.
  • Generally, polysomes are found on the mRNAs that plays key role in cell survival and metabolism.
  • mRNAs that are present in low amount in cells can be identified by the polysomes.
  • Varities in the mRNA translations can be determined by the different configurations of polysomal structures.
  • Polysomal profiling, that measures the activity of polysomes, helps in the estimation of genes expression level.
  • Polysome profiling is also used for the tracking of translational status of an mRNA of known origin and can also give the density of ribosome in cultured cells and tissues.
  • Status of translation of mRNAs in different cells can also be measured through polysomal profiling.

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