In: Biology
Which type of genetic test can be used to identify genetic and chromosomal abnormalities before pregnancy starts?
Amniocentesis |
Newborn screening |
Chorionic villus sampling |
Preimplantation genetic diagnosis |
In vitro fertilization |
Sporadic cancer:
occurs during one's lifetime |
occurs in somatic cells |
affects all cells in the individual |
A and B only |
A, B and C |
Cancer cells are NOT
contact inhibited. |
transplantable. |
invasive. |
de-differentiated. |
immortal. |
What is the purpose of a pharmacogenomic test?
Detection of variants of genes or gene expression patterns affecting drug metabolism |
Design of new pharmaceutical products |
Recommendation of vitamins and dietary supplements based on an individualÕs genotype |
Diagnosis of inherited disease |
Early identification of cancer |
Question 1: Which type of genetic test can be used to identify genetic and chromosomal abnormalities before pregnancy starts?
Preimplantation genetic diagnosis (PGD).
PGD involves genetic profiling of embryos prior to implantation or fertilization.
Other options are wrong.
Amniocentesis & chorionic villus sampling are carried out during pregnancy while new-born screening is carried out after childbirth.
In-vitro fertilization not a method to identify genetic and chromosomal abnormalities at all.
Question 2: Sporadic cancer occurs in somatic cells.
Sporadic cancer occurs in people who don’t have familial history of cancer. Thereby, it doesn’t occur in the autosomal cells (germline cells).
Other options are wrong.
It doesn’t affect all the cells.
People have a risk of developing sporadic cancer on their lifetime, but it is mandatory that all will get sporadic cancer.
Question 3: Cancer cells are NOT contact inhibited.
It is a hallmark of cancer cells. Normal cells halt/inhibit their growth (cell division) when they come in contact with nearby cells. But cancer cells don’t; they keep growing all the sides possible.
Other options are wrong.
Cancer cells are invasive, transplantable, de-differentiated and immortal.
Question 4: Pharmacogenomic test detect variants of genes or gene expression patterns affecting drug metabolism.
Pharmacogenomic test searches for genetic variants associated with various drug metabolism.